Cavaliers vs. Pistons Odds, Spreads, and Total

The Cleveland Cavaliers (59-14) aim to extend their winning streak to four games as they visit the Detroit Pistons (41-32) at Little Caesars Arena tonight at 7 p.m. ET.  The…

DETROIT, MICHIGAN - MARCH 25: Jalen Duren #0 and Lindy Waters III #43 of the Detroit Pistons celebrate against the San Antonio Spurs during the fourth quarter at Little Caesars Arena on March 25, 2025 in Detroit, Michigan. NOTE TO USER: User expressly acknowledges and agrees that, by downloading and or using this photograph, User is consenting to the terms and conditions of the Getty Images License Agreement. (Photo by Nic Antaya/Getty Images)

DETROIT, MICHIGAN – MARCH 25: Jalen Duren #0 and Lindy Waters III #43 of the Detroit Pistons celebrate against the San Antonio Spurs during the fourth quarter at Little Caesars Arena on March 25, 2025 in Detroit, Michigan. NOTE TO USER: User expressly acknowledges and agrees that, by downloading and or using this photograph, User is consenting to the terms and conditions of the Getty Images License Agreement. (Photo by Nic Antaya/Getty Images)

The Cleveland Cavaliers (59-14) aim to extend their winning streak to four games as they visit the Detroit Pistons (41-32) at Little Caesars Arena tonight at 7 p.m. ET. 

The Cavs' offense has stayed hot, as evidenced by a 124-116 victory over the San Antonio Spurs last night. The unit is among the league's best, averaging 122.3 points per game and leading the NBA in three-point shooting percentage at 38.5%. Donovan Mitchell has been instrumental and dropped a double-double against the Spurs 25 points and 14 assists while also gathering eight rebounds.

The Pistons, though, have won four of their last five games, including a 122-96 victory over the Spurs on Tuesday. Marcus Sasser led all scorers with 27 points off the bench. However, Detroit will be without leading scorer Cade Cunningham, who remains sidelined with a calf injury. 

The Cavaliers have dominated recent matchups, winning their last 10 games against the Pistons and leading the current season series 3-0. In their last meeting in January, the Cavs notched a 122-111 win over the Pistons, with Darius Garland leading the team with 27 points, five rebounds, and eight assists.

Spread

  • Cavaliers -6.5 (-107)
  • Pistons +6.5 (-112)

Moneyline

  • Cavaliers -195
  • Pistons +162

Total

  • OVER 227.5 (-110)
  • UNDER 227.5 (-110)

*The above data was collected on March 28, 2025, and may have changed since writing.

  • Cleveland and Detroit are both 2-5 against the spread in their last seven games.
  • The total has gone OVER in five of Cleveland's last six games.
  • The total has gone UNDER in 10 of Detroit's last 11 games against Cleveland.
  • Detroit is 9-1 straight up against Eastern Conference opponents.
  • Cleveland is 10-0 straight up in their last 10 games against Detroit.

Cavaliers vs. Pistons Injury Reports

Cavaliers

  • Ty Jerome, SG - Out
  • Jaylon Tyson, F - Out
  • Evan Mobley, PF - Out
  • Emoni Bates, F - Out

Pistons

  • Cade Cunningham, PG - Out
  • Jaden Ivey, PG - Out

Cavaliers vs. Pistons Predictions and Picks

“Cleveland lost last night to Boston and have the short trip to Detroit in a bounce back spot. The Cavs are 2-0 against Detroit this season with 12 and 19-point wins. At the half, Cleveland led by 8 and 10 points, and that's the angle I like here. Detroit had a day off after a back-to-back and this is the middle of a six-game homestand, so it's not a terrible situation for the Pistons to make this a game in the second-half. Detroit did trail Atlanta by 9 at the half before losing by two points on Monday.” — Vaughn Dalzell, NBC Sports

"Cleveland F Evan Mobley (rest) did not suit up for Thursday's victory and is expected to play in this contest. These two teams rank in the top ten of the league in defensive efficiency, so the under is worth a look. The stronger play is on the Pistons to cover at home. Final Score Prediction, Cleveland Cavaliers win 116-112." — Eddie Klein, Picks & Parlays

The Pistons will try to deny the Cavs from sweeping them in the regular season, but they must bring their A-game because Cleveland is playing great again. Cade Cunningham has missed the last two games with a calf contusion. It's unclear if he will suit up in Friday's game against their Central Division rival, though I expect the coaching staff to put him under minutes restriction if he gets the clearance to play. And although the Pistons have won their last two games without their do-it-all star, Cunningham's value on this young Pistons team will be magnified in this matchup with the No.1 team in the East. The Pistons will need a healthy, productive Cunningham to beat these elite teams from now on." — Lous Aguila, SportyTrader